Hypomethylating agent

Results: 32



#Item
21Eli Lilly and Company / Organofluorides / Carboplatin / Gemcitabine / Ovarian cancer / Hypomethylating agent / Chemistry / Alkylating antineoplastic agents / Ammine complexes

Microsoft PowerPoint[removed]AACR. Fleming et al. Clinical epigenetic resensitization of platinum-rsistant (SGI-110)

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Source URL: astx.com

Language: English - Date: 2014-06-09 09:35:32
22DNA methylation / Methylation / DNA methyltransferase / Epigenome / Histone H3 / Cellular differentiation / Azacitidine / PRC2 / Hypomethylating agent / Genetics / Biology / Epigenetics

Discovery and Development of Next Generation Epigenetic DNMT Inhibitors: Development of SGI-110, a novel DNMT inhibitor 9th International Symposium on Targeted Anticancer Therapies March 7 – 9, 2011 Paris, France

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Source URL: astx.com

Language: English - Date: 2012-12-13 18:06:00
23Nucleosides / Triazines / Medicine / Acute myeloid leukemia / Decitabine / Hypomethylating agent / Leukemia / Oncology / Acute leukemia / Myeloid leukemia

2015_SGI-110_Poster_PW-01_QP-05_ASCPT_Oganesian_Final_2

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Source URL: astx.com

Language: English - Date: 2015-03-06 15:22:40
24Alkylating antineoplastic agents / Ammine complexes / Cisplatin / Carboplatin / DNA methylation / Ovarian cancer / Methylation / Hypomethylating agent / Cancer stem cell / Chemistry / Genetics / Epigenetics

Chemosensitizing Effects of the Novel, Small Molecule DNA Methylation Inhibitor SGI-110 in Ovarian Cancer Abstract #4077

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Source URL: astx.com

Language: English - Date: 2012-12-13 18:06:00
25Myeloid leukemia / Nucleosides / Triazines / Acute myeloid leukemia / Azacitidine / Hypomethylating agent / Decitabine / DNA demethylation / Leukemia / Oncology / Medicine / Acute leukemia

2014_SGI-110_poster_ASCO_abst_7030_Griffiths-draft_v6

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Source URL: astx.com

Language: English - Date: 2014-06-09 09:25:29
26Chemistry / Triazines / Decitabine / DNA methyltransferase / DNA methylation / Myelodysplastic syndrome / Deoxyribose / Deoxyguanosine / Hypomethylating agent / Nucleosides / Medicine / Biology

Scale up and development of a process for a low  volume subcutaneous formulation of SGI‐110, a  potent hypomethylating agent Sanjeev Redkar Astex Pharmaceuticals, Inc., Dublin, CA

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Source URL: astx.com

Language: English - Date: 2012-12-13 18:06:00
27Biology / Methylation / Posttranslational modification / Sodium bisulfite / Chemistry / Epigenetics / Organic chemistry

IN VIVO IMMUNOMODULATORY ACTIVITY OF SGI-110, A SECOND GENERATION HYPOMETHYLATING AGENT, IN HEMATOLOGIC MALIGNANCIES abstract # 680 Alessia

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Source URL: astx.com

Language: English - Date: 2013-07-16 08:37:55
28T cells / CTLA-4

abstract # A256 Epigenetic priming with novel hypomethylating agent SGI-110 improved antitumor activity of CTLA-4 blockade in a syngenic mouse model Alessia

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Source URL: astx.com

Language: English - Date: 2013-12-02 15:45:02
29Nucleosides / Triazines / Azacitidine / lactams / Myelodysplastic syndrome / Decitabine / Acute myeloid leukemia / Lenalidomide / Hypomethylating agent / Medicine / Oncology / Orphan drugs

fall 2010: volume 16, issue 2 newsletter of the myelodysplastic syndromes foundation From the Guest Editor’s Desk Hypomethylating Therapy in

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Source URL: www.mds-foundation.org

Language: English - Date: 2013-09-19 18:49:35
30Triazines / Myelodysplastic syndrome / Syndromes / Azacitidine / Decitabine / Hypomethylating agent / Acute myeloid leukemia / DNA methyltransferase / Lenalidomide / Medicine / Oncology / Nucleosides

Microsoft Word - Decitabine Figure 1.doc

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Source URL: www.ncbi.nlm.nih.gov

Language: English
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